Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS) | Journal of Medicinal Chemistry
Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase | ACS Medicinal Chemistry Letters
Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles | ACS Medicinal Chemistry Letters
Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits | Journal of Medicinal Chemistry
Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit | ACS Medicinal Chemistry Letters
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Discovery of a Highly Selective, Brain-Penetrant Aminopyrazole LRRK2 Inhibitor | ACS Medicinal Chemistry Letters
Discovery of Potent and Selective 7-Azaindole Isoindolinone-Based PI3Kγ Inhibitors | ACS Medicinal Chemistry Letters
Multifunctional Carrier Based on Halloysite/Laponite Hybrid Hydrogel for Kartogenin Delivery | ACS Medicinal Chemistry Letters
MOARF, an Integrated Workflow for Multiobjective Optimization: Implementation, Synthesis, and Biological Evaluation | Journal of Chemical Information and Modeling
Discovery of APD371: Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain | ACS Medicinal Chemistry Letters
Stabilization of Nanoparticles Produced by Hydrogenation of Palladium–N-Heterocyclic Carbene Complexes on the Surface of Graphene and Implications in Catalysis | ACS Omega
Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate | ACS Medicinal Chemistry Letters
Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3-Kinase (PI3K)-γ Inhibitors | Journal of Medicinal Chemistry
Structure and Mechanism-Guided Design of Dual Serine/Metallo-Carbapenemase Inhibitors | Journal of Medicinal Chemistry
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